Predicting the risk of anemia in pregnant women with different somatotypes

  • Tatiana I. Tsidaeva North Ossetian State Medical Academy
  • Kristina G. Tomaeva North Ossetian State Medical Academy
  • Sergey N. Gaidukov St. Petersburg State Pediatric Medical University Ministry of Health of the Russian Federation
  • Nikolai N. Rukhliada St. Petersburg State Pediatric Medical University, Ministry of Healthcare of the Russian Federation
  • Aida A. Cheldieva North Ossetian State Medical Academy
  • Emma G. Plieva North Ossetian State Medical Academy
  • Nataliia G. Salbieva North Ossetian State Medical Academy

Abstract

The aim of the study: to study the frequency of anemia in pregnant women with different somatotypes and to develop a model for predicting the risk of this pathology. Materials and methods. 390 women were examined. Of the women studied 110 were mаcrosomatotype, 173 – mesosomatotype, and 107 – microsomatotype. Somatometry was performed according to R.N. Dorokhov for women in early pregnancy (before 9–10 weeks of gestation). In blood test the level of hemoglobin, red blood cells, and hematocrit is determined using the Medonic M-series hematological automatic analyzer. Serum iron levels were determined colorimetrically with ferrosine. Serum ferritin levels were determined spectrophotometrically using ELISA methods. Results. It was found that iron deficiency anemia was significantly more common in pregnant women of macro-and microsomatic body type compared to women with mesosomatotypes (p < 0.05). Pregnant women with severe anemia were not found. There were iron deficiency anemia of mild and moderate severity, and latent iron deficiency. Hematological parameters (hematocrit, serum iron, serum ferritin) were significantly lower in pregnant women with latent iron deficiency compared to women without anemia (p < 0.05). Using multiple regression analysis, we obtained the regression equation (formula), which predicts the development of iron deficiency anemia in pregnant women of different somatotypes. Conclusions. The calculations according to the presented formula, allows to predict with high accuracy the prognosis of iron deficiency anemia in pregnant women, and also allows to form among patients a high-risk group for the development of this disease in the first trimester of pregnancy when the pregnant woman is registered in the women’s consultation, which will contribute to more effective implementation of therapeutic and preventive measures to prevent the development of this pathology.