Clinical case of a Erythroderma induced by fibrogastroduodenoscopy

Erythroderma – the term used for the description intensive and usually widespread reddening of the skin which has arisen owing to activation of the previous inflammatory dermatosis. Among the causes of erythroderma are the progression of chronic dermatoses, refractory to therapy, medication or inadequate local treatment of dermatoses. In addition, it can be a symptom and/or a sign of systemic diseases (lymphoma, leukemia, tumors of the lungs, intestines and ovaries). Most of the cases of erythroderma described in the literature were induced by taking different types of drugs and dietary supplements. High lethality of this category of patients is associated with both the main disease that caused the development of erythroderma and the nature of emerging metabolic disorders. Erythroderma is one of the most severe conditions that threaten the life of the patient, requiring special approaches in the diagnosis and early treatment. When diagnosing and determining the forms of erythroderma, one of the determining factors is clinical examination and clinical and pathological correlation. Patients with diseases of a digestive tract have high risk of development of side effects from intake of drugs and carrying out tool methods of a research. One of the screening methods of a research is the fibrogastroduodenoskopy (EGD). We provide the description of the first case in our practice of the patient with the erythroderma which has arisen after the EGD-research. Questions of pathogenesis, differential diagnostics of an erythroderma on the basis of a clinical picture and histological signs with illustrations are also discussed.