Становление микробиоты толстого кишечника новорожденных при различных способах родоразрешения

Юлия Лазаревна Набока; Александр Николаевич Рымашевский; Этери Гонериевна Свирава; Лариса Ивановна Васильева; Лидия Елисеевна Брагина; Марина Леонидовна Черницкая; Ксения Теймуразовна Джалагония

Development of microbiota in the large intestine of newborns depending on various delivery methods

Yuliya Lazarevna Naboka Rostov State Medical University of the Russian Federation Ministry of Public Health
Aleksandr Nikolayevich Rymashevskiy Rostov State Medical University of the Russian Federation Ministry of Public Health
Eteri Goneriyevna Svirava Rostov State Medical University of the Russian Federation Ministry of Public Health
Larisa Ivanovna Vasilyeva Rostov State Medical University of the Russian Federation Ministry of Public Health
Lidiya Yeliseyevna Bragina Rostov State Medical University of the Russian Federation Ministry of Public Health
Marina Leonidovna Chernitskaya Rostov State Medical University of the Russian Federation Ministry of Public Health
Kseniya Teymurazovna Dzhalagoniya Rostov State Medical University of the Russian Federation Ministry of Public Health

Abstract

We have examined 96 conditionally healthy primigravidae and 96 newborns. Group 1 (n = 51): gravidae with normal course of preg-nancy and delivery, group 2 (n = 45): gravidae with normal course of pregnancy and deliveries by caesarian section (indications for the operation - severe myopia), group 3 (n = 51): newborns from gravidae of group 1, group 4 (n = 45): newborns from gravidae of group 2. Purpose: study of the development of microbiota in the large intestine of newborns depending on various delivery methods. Enterococcus sp. (58,2 %), S. epidermidis (55,7 %), Corynebacterium sp. (53,1 %), E. coli (41,7 %) dominated in meconium microbiota. By the day 5 in group 3 we registered more frequently (p < 0,05) Bifidobacterium sp., Corynebacterium sp., E. coli, in group 4 - Klebsiella sp. Independently from the delivery method, by day 5 we observed in the feces of newborns increased (р < 0,5) content of Bifidobacterium sp., Lactobacillus sp., E. coli, Enterococcus sp., and S. aureus.