Diagnostics and prevention of infections caused by Streptococcus agalactiae in pregnant women and newborn infants

  • Svetlana L’vovna Zatsiorskaya D. O. Ott Research Institute of Obstetrics and Gynecology RAMS
  • Anna Alexandrovna Krysanova D. O. Ott Research Institute of Obstetrics and Gynecology RAMS
  • Vladislav Olegovich Khvan Saint Petersburg state Maternity hospital N 18
  • Zinaida Mikhailovna Martikainen D. O. Ott Research Institute of Obstetrics and Gynecology RAMS
  • Alevtina Mikhailovna Savicheva D. O. Ott Research Institute of Obstetrics and Gynecology RAMS

Abstract

The study investigates colonization of the genitourinary tract and rectum in pregnant women by Streptococcus agalactiae in early pregnancy, as well as pregnancy outcomes for mother and infant depending on the use of antibiotic prophylaxis. The frequency of GBS colonization was 15.9 %, with the detection rate in urine being 8.6 %, in the vagina - 3.5 %, in the rectum - 10 %. The efficiency of amoxicillin/clavulanic acid administered in the II trimester was 66.7 %. Pregnancy outcomes in women receiving and those not receiving antibiotic prophylaxis were studied. In all women receiving amoxicillin/clavulanic acid term labor occurred, with healthy full-term infants born. In one woman not receiving antibiotic prophylaxis there was preterm labor at 34 weeks of gestation.