Biomechanical lung characteristics depending on the clinical and laboratory status of newborns in critical state

Effectiveness estimation and correction of respiratory support parameter is one of the most important issues of the modern neonatology. The aim of the study was to investigate the correlation between indicators of biomechanical properties of respiratory system, patient clinical status and laboratory data. It was found that the respiratory system compliance, the lung overdistention coefficient and the time constant correlate with clinical and laboratory indicators of patient status. They were shown to be the key indicators of lung biomechanics, they reflect the severity of lesions, the effectiveness and necessity of parameter correction of the therapy of the respiratory system.