Role and place of DNA diagnostics in infection clinics
Abstract
The review article is addressed to general pediatricians. It considers common approaches, technical principles and applications of DNA polymerase chain reaction (PCR) usage in clinical microbiology. Comparative significance of immunological (antigen-based) and PCR/nucleic acid based diagnostics for detection of various viral, protozoan and bacterial infections is discussed. PCR applications are considered for diagnostics of different infectious diseases, e. g., viral hepatitis, sexually transmitted diseases, some zoonotic infections.
