Metabolic syndrome and morphofunctional state of pancreas in children: clinical and pathogenetic relationship

The aim of the study: evaluation of pancreatic morphofunctional state of children with metabolic syndrome (MS). 48 children were examined with different shapes and degrees of obesity, ranging in age from 6 to 15 years old (23 males and 25 females). 2 selected groups: core group-31 child with MS, the comparison group-17 children with obesity without signs of MS. Decrease the postprandial response of the pancreas, which indicates lower adaptive capacity and high risk of development of chronic pancreatitis in children with MS. The interrelation between the overall size of the gland before and after food load with violations of carbohydrate and lipid metabolism. The results indicate the need for in-depth surveys of children with a view to the correction of excretory and endocrine functions of the pancreas decrease in risk of formation of MS