PROGNOSTICATION OF BILATERAL NEPHROLITHIASIS DEVELOPMENT RISK

  • Nair Sabirovich Tagirov Saint-Petersburg State Pediatric Medical University
  • Andrey Glebovich Vasilyev Saint-Petersburg State Pediatric Medical University
  • Nariman Kazikhanovich Gadzhiev A. M. Nikiforov Federal Russian Center for Emergency and Radiation Medicine
  • Alexander Zinovievich Lihtshangof Saint-Petersburg State Pediatric Medical University

Abstract

The study involved 653 patients with nephrolithiasis. A multivariate based on discriminant analysis model predicting the risk of bilateral nephrolithiasis development was constructed. Clinical testing revealed high ability of the proposed mathematical model for predicting the development of bilateral nephrolithiasis. The relative risk criterion is highly informative to predict the risk of bilateral nephrolithiasis development. The signs of the high-risk are: urine pH rise over 6.1, concentration of the urine magnesium decrease under 2.26 mmole/l, level of the urine saturation with calcium oxalate over 3.27 and the relative tubular reabsorption under 97.5 %.