PATHOGENETIC MECHANISMS OF STRESS CARDIOMYOPATHY IN HIGH-QUALIFIED SPORTSMEN

Hormonal and immune disturbances were investigated in high-qualified sportsmen during different periods of training cycle. Changed correlation of cortisol and testosterone levels was revealed. This fact is directly associated with significant immune dysfunction of Tand B-systems which leads to progression of cellular and humoral autoimmune reactions. These changes occure in the transitional period of the training cycle. It was confirmed that autoimmune reactions may be considered as the earliest markers of stress cardiomyopathy. Those sportsmen who develop these reactions must be classified as a risk-group.