Варианты патологических изменений стоп у детей с синдромом Клиппеля–Треноне различной степени тяжести: ОРИГИНАЛЬНЫЕ СТАТЬИ

Александр Григорьевич  Веселов; Виктор Владиславович  Набоков; Ольга Николаевна  Васильева; Елена Вячеславовна  Терехина; Наталья Анатольевна  Веселова

doi:10.56871/PED.2025.24.73.004

Variants of pathological changes of feet in children with Klippel–Trenaunay syndrome

ORIGINAL STUDIES

Alexander G. Veselov Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia
Victor V. Nabokov Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia
Olga N. Vasilieva Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia
Elena V. Terekhina Saint Petersburg State Pediatric Medical University, Saint Petersburg, Russia
Natalya A. Veselova Clinic “Energy of Health”, Saint-Petersburg, Russia

Keywords:

гигантизм синдром Клиппеля–Треноне множественные ангиокератомы «портвейные» пятна деформации стоп gigantism Klippel–Trenaunay syndrome multiple angiokeratomas port wine spots foot deformities

Abstract

Background. The severity of foot deformities in embryonic type dysplasia of the great veins of the lower extremities (Klippel–Trenaunay syndrome) varies depending on the severity of vascular damage. Hypertrophy of the limbs or individual segments can range from insignificant to extremely pronounced. Klippel–Trenaunay syndrome is often combined with orthopedic pathologies such as macro- and microdactyly, syndactyly, flat feet, and contractures.

Aim — to analyze the variants of pathological changes in the feet in children with Klippel–Trenaunay syndrome of varying severity.

Materials and methods. The work is based on the results of examining 73 patients with embryonic type dysplasia of the great veins (ETMGV) aged from 0 to 18 years, who were treated from 2014 to 2024. According to the severity of the pathology, four groups of patients were identified — with mild, moderate, severe and extremely severe degrees of ETMGV (Klippel–Trenaunay syndrome includes only moderate, severe and extremely severe degrees of ETMGV).

Data processing was performed using the STATISTICA 6.0 and Excel2007 computer programs.

Results. Patterns of increase in the length and circumference of the feet in patients with Klippel–Trenaunay syndrome were determined. Statistical analysis of the average difference in foot lengths and the asymmetry coefficient was performed in groups of patients compiled in accordance with the severity of the syndrome. An increase in the severity of foot length asymmetry was found with an increase in the severity of Klippel–Trenaunay syndrome. As a result of examination of 73 children, equinus contracture of the feet of the affected limb was detected by us in 5 patients (6.84%), of which 2 (2.7%) had a severe degree, and 3 (4.1%) had an extremely severe degree. Split foot was detected in one patient (1.4%) with a severe degree. “Spherical” foot shape was detected in 3 children (4.1%) with an extremely severe degree of the syndrome.

Conclusions. Changes in the length and circumference of the foot of the affected lower limb in patients with Klippel–Trenaunay syndrome are directly dependent on the severity of the syndrome. Correlations were determined between the severity of the syndrome and an increase in the size of the limbs (calf circumference, thigh length and overall limb length, foot length and circumference, calf length and thigh circumference). Variants of changes in the feet were identified according to the degree of expression of cosmetic changes and changes that impair their function.

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