Heart rate variability analysis with daily monitoring of electrocardiograms in children with chronic non-obstructive pyelonephritis

Condition of the autonomic nervous system reflects the characteristics of the autonomic regulation of the activities of various functional systems. In order to determine possible violations of the autonomic regulation of the functional activity of the urinary system there was held some timing and spectral parameters of heart rate variability of 53 children aged 7 to 14 years old with chronic unobstructive pyelonephritis. The diagnosis of chronic obstructive pyelonephritis was set in accordance with the code N11.0 ICD-10. The control group consisted of 30 almost healthy children. In order to investigate the autonomic regulation of examined children’s urinary system vegetative status was determined using Holter ECG according to a standard procedure. By use of the complex DX-AKM-03ArNika (Kharkiv, Ukraine) registration of bioelectric potentials formed as electrocardiointervals was provided. Based on the results obtained, a database was developed, further analyzed in the computer program ArNika V 2.0 (Medibase). As a result of the survey of children with chronic unobstructive pyelonephritis established the presence of autonomic dysfunction with a predominance of sympathetic over parasympathetic component. This children’s chronic unobstructive pyelonephritis is characterized by initial vegetative tone in form of sympathicotonia, vagotonia and amphotonia, which is a prerequisite for searching for methods of individualizing treatment approaches depending on the vegetative tone.